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International Symposium on Primo-Vascular System

Special Topics on Cancer, Regeneration, and Aupuncture

Date / September 17 (Friday) - 18 (Saturday), 2010
Venue< / Cheongpung Resort-Lake Hotel, Jecheon, Korea
Organizing Committee
Chair:

Kwang-Sup Soh (Seoul National University)

Vice-Chair:

Chong-Kwan Cho (Dunsan Oriental Hospital, Daejeon University).

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8:00 Opening Remarks Kwang-Sup Soh, Organizer, Department of Physics & Astronomy, Seoul National University, Korea
"Introduction to Primo-System"
8:15-9:30 Primo System-I
Co-Chairs: Eduard Van Wijk, Jongyoung Kim
PS-1 Byung-Cheon Lee, Ph.D. / Director, Pharamacopuncture Medical Research Center, Korea
"Network of Primo-Vessels and Nodes Floating inside the Bovine Heart"
PS-2 Weibo Zhang, Ph.D./Prof., Institute of Acupuncture & Moxibustion, China Academy of Chinese Medical Science,
"Finding a Novel Threadlike Structure on the Intra-abdominal Organs Surgace of Small Pigs by Using In-vivo Trypan Blue Staining"
PS-3 Chae Hun Leem, M.D./Ph.D./Prof., College of Medicine, University of Ulsan, Korea
"Comparison of Primo-system and Similar-looking Artifacts"
PS-4 Yeonhee Ryu, Ph.D./Senior Scientist, Korea Institute of Oriental Medicine, Korea
"Morphological Study of Primo-Vascular Sub-duct Structure"
PS-5 Sae Young Ahn, Ph.D./Adjunct Prof., Department of Physics & Astronomy, Seoul National University, Korea
"An Effect of Primo-System on Liver Tissue Recovery after Irreversible Electroporation"
9:30-10:00 Coffee Break
10:00 - 10:30 Opening Ceremony Welcoming Speech
Soo Sung Lee, Chairman of the 2010 World Oriental Medicine-Bio EXPO in Jecheon, Korea Organization Committee Congratulatory Remarks:
Myeong Hyeon Choi: Mayor, Jechon City, Korea Jae Ill Byun: Chairman of the Education, Science and Technology Committee National Assembly Jeong-gon Kim, President of the Association of Korean Oriental Medicine
10:30 - 11:00 Keynote Lecture-I(Introduced by Kyung A. Kang) Ca-1 Donald M. Miller, M.D./Ph.D./Prof./Director, James Graham Brown Cancer Center, University of Louisville, USA
11:00 - 12:00 Cancer-I
Co-Chairs: Paula J. Bates, Yoshiharu Motoo
Ca-2 Mei-Yu Hsu, M.D./Ph.D./Assistant Prof., Department of Pathology, Program in Dermatopathology, Brigham and Women's Hospital, Harvard Medical School, USA
"Melanoma Morphogenesis: Significance of Vasulogenic Mimicry and Perivascular Niche"
Ca-3 Tae Young Han, O.M.D./Head Doctor, Banryong Herb Clinic, Korea
"Anti-tumor Activity of MSB0052, a Novel Korean Medicine, in Murine Melanoma Models and Relations to Composition Changes of Primo-system"
Ca-4 Peter W. Vaupel, M.D./Ph.D./Prof. Emeritus., Department of Radio-Oncology and Radiotherapy, University Medical Center, Germany
"Oxygen Transport to Tumors: Pathophysiology and Clinical Implications"
Ca-5 Byung S. Kwon, Ph.D./Distinguished Investigator, National Cancer Center, Korea
"Adoptive CTL Therapy against Cancers"
12:00 - 13:30 Lunch
13:30 - 15:15 Medical Imaging Co-Chairs: Hyeran Lee, Sang Suk Lee
MI-1 Samuel Achilefu, Ph.D./Prof., Department of Radiology, School of Medicine, Washington University in St. Louis, USA
"Delivery Strategies for Imaging Primo-Vascular System"
MI-2 Sang Joon Lee, Ph.D./Prof., Department of Mechanical Engineering, Pohang University of Science and Technology, Korea
"How to Measure Bio-dynamics of Primo-System?"
MI-3 Kyung A. Kang, Ph.D./Prof., Chemical Engineering Departments, University of Louisville, USA
"Mapping Primo-Vascular System by Molecular Imaging with Contrast Agents"
MI-4 Paula J. Bates, Ph.D./Associate Prof., James Graham Brown Cancer Center, University of Louisville, USA
"Aptamers: Opportunities for Use in Cancer Therapy, Molecular Imaging, and as Tools to Study the Primo-Vascular System"
MI-5 Jin-Kyu Lee, Ph.D./Prof., Department of Chemistry, Seoul National University, Korea
"Photostable and Biocompatible Fluorescent Silica (f-SiO2) Nanoparticles"
MI-6 Sungjee Kim, Ph.D./Associate Prof., Department of Chemistry, Pohang University of Science and Technology, Korea
"Multiplexed and Deep Penetration In Vivo Imaging using Infrared Emitting Nanoparticles"
MI-7 Young-Tae Chang, Ph.D./Associate Prof., Department of Chemistry, National University of Singapore, Singapore
"Bioimaging of Stem Cells, Live Tissue and Whole Animals using Diversity Oriented Fluorescence Library Approach (DOFLA)"
15:15 - 15:45 Coffee Break & PosterPresentation / Discussion
15:45 - 17:00 Oxygen & Physiology Co-Chairs: David Harrison, Hesson Chung
OP-1 David K. Harrison, M.D. / Ph.D / Honorary Senior Lecturer, Institute of Cellular Medicine, Newcastle University, UK
"The clinical Application of Optical Spectroscopy in Monitoring Tissue Oxygen Supply following Cancer Treatment"
OP-2 Youngmi Lee, Ph.D./Associate Prof., Department of Chemistry and Nano Science, Ewha Womans University, Korea
"Oxygen Measurements on Acupucture Points Using an Electrochemical Oxygen Microsensor"
OP-3 Chin Ok Lee, Ph.D./Adjunct Prof., Laboratory of Cardiac & Membrane Physiology, The Rockefeller University, USA
"PKA Activation Affects the Voltage Dependence of Na-K ATPase Pump and Na-Ca Exchange Currents in Cardiac Myocytes Differently"
OP-4 Pan Dong Ryu, D.V.M./Ph.D./Prof., Pharmacology, College of Veterinary Medicine, Seoul National University,
"Electrophysiological Properties of Cells in Primo-Tissues on Organ Surface of Abdominal Organs in Rats"
OP-5 Hyung Soon Park, Ph.D./Adjunct Prof., ProBiond Co., Ltd, Konkuk University, Korea
"Proteomic Analysis of Primo-Vessels and Primo-Liquid"
17:00 - 17:15 Coffee Break
17:15 - 18:30 Acupuncture Co-Chairs: Eun-Young Lee, Weibo Zhang
AP-1 Eduard Van Wijk, Ph.D./Senior Scientist, Sino-Dutch Center for Preventive and Personalized Medicine, Leiden University, The Netherlands
"Unusual Optical Properties of Collagen and Implications for the Primo-Vascular System"
AP-2 Yuan Lin, M.D./Ph.D./Prof., Department of Anatomy, Southern Medical University, China
"From the Anatomical Discovery of Meridians and Collaterals to Fasciaology Theory"
AP-3 Moriya Ohkuma, M.D./Ph.D./Prof., Department of Dermatology, School of Medicine, Kinki University, Sakai Hospital, Japan
"Oriental Medicine in Japan, Lymphology, and Primo-Vascular System"
AP-4 Christopher J. Zaslawski, Ph.D./Associate Prof./Director, College of Traditional Chinese Medicine, Department of Medical and Molecular Biosciences, University of Technology, Sydney, Australia
"An Evidence-based Review of Acupuncture as an Adjunctive Therapy in Comprehensive Cancer Care"
AP-5 Seung-Ho Yi, Ph.D./Assistant Prof., Acupuncture and Meridian Science Research Center, Kyung Hee University, Korea
"Thermal Characteristics of Moxibustion with Various Air Flows and its Ingredients, and its Implication to Primo-Vessels"
18:30 - 19:00 Coffee Break
19:00 - 21:00 Gala Party Convention Hall Introduction and Announcement by Michael Potraz
Appreciation plaque - Byeong-jun Sohn, President of Mobase Co., Ltd
Congratulatory Remarks - Byeong-jun Sohn, President of Mobase Co., Ltd
Words of Encouragement - Jae Gap Kim, Secretary General of the 2010 World Oriental Medicine-Bio EXPO in Jecheon, Korea Organization Committee, In-Chul Sohn, Prof., College of Oriental Medicine, Wonkwang University, Korea, Daein Kang, President of Korean Pharmacopuncture Institute Korean Martial Arts Performance

SEPTEMBER 18th (SATURDAY)

8:00 - 9:00 Primo System - II
Co-Chairs: Moriya Ohkuma, Pan Dong Ryu
PS-6 Min Su Kim, D.V.M./Ph.D./Assistant Prof., Department of Veterinary Surgery and Traditional Veterinary Medicine, College of Veterinary Medicine, Chonbuk National University, Korea
"X-ray Microscopic Study of Primo-Vessel"
PS-7 Minah Suh, Ph.D./Associate Prof., Department of Biological Sciences, Sungkyunkwan University, Korea
"Heterogeneity of Tissue Oxygenation and its Relationship with Primo-System of Murine Melanoma Cancer"
PS-8 Satoru Fujiwara, D.M.D./Former Prof., Department of Anatomy, Osaka City University, Japan
"Pioneering Research on Primo-System in Japan"
PS-9 Jong-Su Lee, MD./Former Head Doctor of 'Lee Jong Su Clinic' in Korea and Provincial Hospital in Japan
"Recollection of Early Research on Primo-System"
9:00 - 9:30 coffee Break
9:30 - 10:00 Keynote Lecture - II
(Introduced by
Minah Kim)
Ca-6 Larry W. Kwak, M.D./Ph.D./Prof., Department of Lymphoma & Myeloma, Division of Cancer Medicine, The University of Texas M. D. Anderson Cancer Center, USA
"Therapeutic Vaccines for Lymphoma: A Tale of Bench to Bedside Translation"
10:00 - 11:00 Cancer-II
Co-Chairs: Peter Vaupel, Byung S. Kwon
Ca-7 Chang-Hoon Nam, Ph.D./Leader, Interdisciplinary Human Biotechnology Group, Korea
Institute of Science and Technology Europe, Germany
"An Antibody Inhibitor of the LMO2-Protein Complex Blocks its Normal and Tumorigenic Functions"
Ca-8 Yoshiharu Motoo, M.D./Ph.D./Prof., Department of Medical Oncology, Kanazawa Medical University, Uchinada, Japan
"Stress Responses of Pancreatic Cancer Cells and Their Significance in Invasion and Metastasis"
Ca-9 Gi-Ming Lai, M.D./Associate Prof., Cancer Center, Taipei Medical Univ/-Wan Fand Hospotal & Shuang Ho Hospital, Taiwan
"Human Urine Extract (CDA-2) Eliminates Cancer Stem-Like Cells and Inhibits Metastasis - Its Potential Role on the Microenvironment of Primo-System"
Ca-10 Mison Chun, M.D./Ph.D./Prof., Department of Radiation Oncology, School of Medicine, Ajou University, Korea
"Experience with Traditional Medicine for Cancer Patients at Ajou University Hospital"
11:00 - 11:30 Keynote Lecture - III
(Introduced by Minah Kim)
Ca-11 Kurt Zaenker, M.D./D.V.M./Ph.D./Prof., Institute of Immunology & Experimental Oncology, University Witten/Herdecke, Germany
"Cancer Cell Metastasis: Invitation to a Second Round"
11:30 - 13:00 Lunch
13:00 - 14:30 Re-1 Magdalena Kucia, Ph.D./Assistant Prof., Stem Cell Institute, James Graham Brown Cancer Center, University of Louisville, USA
"Very Small Embryonic/Epiblast Like Stem Cells in Adult Tissues - Challenge for Regenerative Medicine"
Re-2 Vyacheslav Ogay, Ph.D./Leading Researcher, Laboratory of Immunochemistry and Immunobiotechnology, National Center for Biotechnology of the Republic of Kazakhstan, Kazakhstan
"Identification and Characterization of Small Stem Like Cells in the Primo-Vascular System of Adult Animals"
Re-3 Kyung-Sun Kang, D.V.M./Ph.D./Prof., College of Veterinary Medicine, Seoul National University, Korea
"The Secret Lives of Stem Cells: Unraveling the Molecular Basis of Stem Cells Aging"
Re-4 Hee Min Kwon, Ph.D./Adjunct Prof., Department of Physics & Astronomy, Seoul National University, Korea
"Histological Comparison of Primo-Nodes and Lymph Nodes of Rat"
Re-5 Seong Hun Ahn, O.M.D./Ph.D./Assistant Prof., Department of Meridian & Acupoint, College of Oriental Medicine, Wonkwang University, Korea
"Primo-Microcell in Primo-Node as One Possible Origin of Adult Stem Cells: May be Sanal Theory is Right"
Re-6 Sin-Soo Jeun, M.D./Ph.D./Prof., Department of Neurosurgery, The Catholic University of Korea, Korea
"Pathotropism of Mesenchymal Stem Cells for Cellular Therapy in CNS Diseases"
14:30 - 15:30 Coffee Break & Poster Presentation / Discussion
15:30 - 17:00 Panel Discussion

Future Direction for Primo-System Research - Short and Long Terms
Session Introduction and Announcement by Kyung A. Kang
Chairs: Peter W. Vaupel and Kwang-Sup Soh

Panelists:
Primo-System(PS) - Pan Dong Ryu
Cancer(Ca) - Larry W. Kwak
Medical Imaging(MI) - Samuel Achilefu
Oxygen & Physiology(OP) - David Harrison
Acupuncture(AP) - Christopher J. Zaslawski
Regeneration(Re) - Magdalena Kucia
17:00 - 19:00 Closing Ceremony, Farewell Dinner, and Poster Competition Awards
Words of Encouragement
- Kiok Kim, President of Korea Institution of Oriental Medicine
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Poster Presentation Index

Primo-System

PS-01. A Novel Model for Acupuncture Meridian: Primo-System (Bonghan System) Combined with Fascia (Primo-Fascia Model) / Byung-Cheon Lee I 138
PS-02. Fine Structures of the Fibers in Primo-Nodes and Vessels / Jong Hyun Jung I
140 PS-03. Three Dimensional Reconstruction of Blood Vessel Networks in Abdominal Skin of Rats for Matching the Primo System / Jungdae Kim I 141
PS-04. Color of Postmortem Tissues at Acupuncture Points in Cryosection Image Dataset of Visible Human Project / Jungdae Kim I 142
PS-05. Primo-System Applied Research Outline / Michael Potroz I 143
PS-06. Primo-System in Mesentery / Ping An I 144
PS-07. A Study on the Process of Refuting and Disusing the Bonghan Theory through Publication Review / Sang Hun Lee I 145
PS-08. Identification of Keratin 10 in Rat Primo-Vascular Tissue on Surface of Abdominal Organs / So Rim Kim I 146
PS-09. Development of a Laparoscopic System for In Vivo Observation of the Primo System / Sungwoo Lee I 147
PS-10. Using Trypan Blue to Visualize the Primo-System on the Dog's Intestinal Surface / Wen-hui Yu I 148
PS-11. Morphological Discrimination of the Differences between Fibrin String and Internal Organ-surface Primo-Vessels / Wen-Ji Zhang I 149
PS-12. Observation with Fluorescent Nanoparticles of the Primo-System along the Sciatic Nerve from Zusanli (ST-36) / Zhao-Feng Jia I 151
PS-13. A Modified Method to Distinguish Primo Vessels in the Mesentery from Vascular Vessels and Lymphatic Vessels / Zhendong Su I 152
PS-14. Atomic Force Microscopy Study of Primo-Microcells / Ku Youn Baik I 153
PS-15. Visualization of Putative Primo System on the Vitelline Membrane and in Albumin of Chicken Egg by using Trypan blue staining / Seung-Yoon Lee I 154
PS-16. Network of primo-vascular system on superficial fascia in the location of an acupuncture meridian / Baeckkyoung Sung I 155

Electrophysiology of Primo-System

PS-17. A Slice Preparation of Rat Organ Surface Primo-Node / Chae Jeong Lim I 158
PS-18. Spontaneous Action Potentials from the Primo-System / Cheon-Joo Choi I 160
PS-19. TEA-sensitive Currents in Single Cells Recorded from Rat Primo-Node Slices / Jae-Hong Choi I 161
PS-20. Normalized Fourier Transform for Analysis of Primo-vessel's Action Potential / Seong Jin Cho I 162

Cancer and Primo-System

PS-21. Primo-System Contribution on Tumor Regression with Irreversible Electroporation / Hong-Bae Kim I 166
PS-22. Compositional Differences of Primo-, Blood, and Lymphatic Vascular System in Lung Cancer Xenograft / Jung Sun Yoo I 167

Alternative and Oriental Medicine

PS-23. The Effect of the Gongjindan Ectract on the Hepatocarcinogenesis Induced by N-Nitrosodiethylamine in Rats / Geun-young Seo I 170
PS-24. In vivo PIV Measurements of Blood Flow in a Stenosed Micro-scale Blood Vessel / Hojin Ha I 171
PS-25. Antioxidant Activity of Solvent Fraction from Gongjindan / Hyo-jeong Ban I 173
PS-26. Magnetic Property and Capture Status of Red Blood Cell depending on Static or Pulse Low Magnetic Field / Jong-Gu Choi I 174
PS-27. Study for Weight Loss and Side Effects of Short Term, High Dose Administration of Herba Ephedrae in SD-Rats / O Sang Kwon I 176
PS-28. Substandard Rate of Ear Acupuncture Needle under Stereoscopic Microscope / Sae Bhom Lee I 177
PS-29. Xenograft of Human Cancer Cells for Inducing Angiogenesis in Zebrafish Embryos / Eunseok Seo I 179
PS-30. Apoptotic Cardiomyocyte Beating Detected with Spectrometer of Intensity Fluctuations / Svetlana Norina I 180
PS-31. Therapeutic Effect of MSB0052 on Recurred Lymphoplasmacytic Lymphoma and Malignant Melanoma Case Reports / Tae Young Han I 181
PS-32. Therapeutic Effect of MSB0052 on Recurred Breast Cancer of Shao - Yin Type and the Effect of Selecting Western Chemodrugs by Classification of Sa-sang Phenotyping Methodology / Tae Young Han I 182
PS-33. Therapeutic Effect of MSG500 on Tai-yin Type Cancers of Childrens, Malignant Peripheral Nerve Sheath Tumor, Myofibroblastoma, Inflammatory Myofibroblastic Tumor / Tae Young Han I 183
PS-34. Therapeutic Effect of MSG500 on Tai-yin Type Cancers: Inoperable Colon Cancer, Renal Cell Carcinoma, and Hepatoma / Tae Young Han I 184
PS-35. Chinese Medicine Tongue Inspection: An Examination of the Practitioner Reliability for Specific Tongue Characteristics / Minah Kim I 185

Others

PS-36. New Flow Path from the Testis to the Abdominal Organ via Primo-system / Hyun-Jung Han I 188
PS-37. Cancer Cell Migration via the Primo-system: Intratesticular Inoculation of Fluorscent Nanoparticles-labeled NCI-H460 Cells / Hyun-Jung Han I 189
PS-38. Isolation of the Primo-Vessels in the Rodent Thoracic Lymphatic Ducts by using Lymphatic-Specific Fluorescent Transgenic Mouse / Young-Kwon Hong I 190
PS-39. Endothelium and Mesenchymal Feature of Primo-Vessels in the Mesentery / Ping An I 191
PS-40. Tracing Primo-Vessels in the Mesentery / Zhendong Su I 192